Illinois State Police investigated a four-vehicle crash Wednesday north of Georgetown on Illinois Route 1 and Vermilion County Road 900 North.
Police said the accident occurred at 7:47 a.m. when a southbound Ford Focus struck the rear of a Toyota Camry, which caused the Camry to run off the road. The Focus then struck the rear of a GMC Sierra, which caused the Sierra to cross into the northbound lane and hit a northbound Chevrolet Equinox head-on.
The 29-year-old driver of the Focus, from Danville, and a 7-year-old Danville boy riding in the car were taken to a local hospital with life-threatening injuries, police said.
The drivers of the Camry, a 40-year-old man from Oakwood, and the Equinox, a 20-year-old man from Georgetown, were taken to an area hospital with non-life threatening injuries.
All those involved were wearing seat belts, and police have not the names of those involved.
The accident caused Route 1 to be closed until about 3 p.m. Wednesday.
Police continue their investigation.